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KMID : 0379120040320020142
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Korean Journal of Mycology
2004 Volume.32 No. 2 p.142 ~ p.144
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Determination and Characterization of Inhibitory Activity of Mycelial Extracts from Several Korean Mushrooms against Helicobacter pylori
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Lee Jae-Kyoung
Yoon Jeong-Weon
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Abstract
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The effect of hot water and methanol extracts of 9 species from Korean mushrooms (Fomitopsis pinicola, Fomitella traxinea, Codyceps militaris, Phellinus linteus, Coriolus versicolor, Sparassis crispa, Ganoderma lucidum, Fomes fomentarius, Agaricus blazei) on the growth of Helicobacter pylori were examined using a Mueller-Hinton agar diffusion method. Hot water ($121^{\circ}C$) extracts from fruit bodies of F. traxinea, C. militaris, P. linteus, C. versicolor and F. pinicola showed $10{\sim}15\;mm$ inhibition zone against H. pylori. Methanol extracts of F. pinicola showed 44 mm inhibition zone, but another extracts showed no inhibition. Early fractions of DEAE-Sephadex A-25 column chromatography of methanol extracts from F. pinicola showed high inhibition activity against H. pylori.
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KEYWORD
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Fomitopsis pinicola, , Helicobacter pylori, Inhibition, Mushroom
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